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| Cdc42GTP 小鼠单克隆抗体 |
| 货号: 26905 |
| 规格: 30 µL |
| 基因符号: CDC42 |
| 描述: Cdc42-GTP Monoclonal Antibody |
| 背景: Small GTPases are a super-family of cellular signaling regulators. Cdc42 GTPase belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs). |
| 免疫原: Recombinant full length protein of active Cdc42 |
| 经过测试的应用: IP, IHC and IF (Not applicable for WB since SDS denatures the Cdc42GTP) |
| 引用文献的应用: IF, IHC; Click for Details – Part 01 Part 02 |
| 推荐稀释度: IP: 1 µg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250 |
| 浓度: 1 mg/ml |
| 种属反应性: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG1 |
| 纯化:: Purified from ascites |
| Preservative: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: Cdc42-GTP monoclonal antibody recognizes active Cdc42 from vertebrates. |
| 储存条件:: Store at -20°C. Avoid repeated freezing and thawing |
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